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SKIN IN ADOLESCENCE: ORAL THERAPY FOR ACNE
Most people with moderately severe acne require oral treatment in combination with creams. The main forms of oral therapy include antibiotics, hormone treatment and Ro-Accutane (Isotretinoin).
Oral antibiotics
Until recently oral antibiotics were the mainstay of treatment for moderate to severe acne. Generally speaking, they are very successful in treating acne, and have minimal side effects.
One common myth about antibiotics is that they lead to thrush in the bowel, which leads to chronic illness. Although antibiotics do increase the incidence of vaginal thrush, this is only a temporary phenomenon. They do not cause long-term illnesses. It is also sometimes believed that if antibiotics are taken for acne they will not work for more serious infections, which is not the case.
The most commonly used antibiotics include tetracycline, minomycin, erythromycin and Bactrim. Usually, antibiotics need to be taken for a period of at least three months before any benefit is seen, and they need to be used on a prolonged basis as they do not ‘cure’ acne. The mainstay of therapy with antibiotics is therefore to suppress the acne until it spontaneously improves. The main limitation of antibiotics is that they are not effective in cases of severe cystic acne and become less effective with time, as resistance occurs.
Most people tolerate antibiotics very well but may be fearful of taking them for a long time, despite their safety and effectiveness. (Exceptions here are the tetracyclines, which should not be taken by children under eight as they can stain the teeth and accumulate in developing bones. Likewise, although Erythromycin is safe during pregnancy, other antibiotics should not be taken during this time.)
*22/150/5*

