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DRUGS USED IN TREATMENT AFTER CORONARY ARTERY BYPASS SURGERY
Beta-blocking drugs
There are several of these, of which the most commonly used are atenolol and metoprolol. They are used to lower blood pressure and to control pulse irregularity, and they may also have been used before the operation to control or prevent angina.
Their most important adverse side effect is that they can provoke asthma in those who are prone to it.
Asthma represents a contraindication to further use of the drug. Beta-blockers can also make your limbs cold. (Coldness in the limbs is quite common after the operation for a time, even amongst those who are not taking a beta-blocker.) In some people beta-blockers cause reduced psychological responses (or blunting) and loss of energy. Psychological blunting and loss of energy, you will recall, are common after operations even without treatment with these drugs. Thus, in some cases, it may be an after effect of the operation, rather than the beta-blocker, which is causing the apparent side effect.
Calcium channel blockers
Verapamil, diltiazem, nifedipine, felodipine and others are used to lower blood pressure. Sometimes they are given to control cardiac irregularities and they may have been used to suppress angina before the operation. They are an alternative to beta-blockers, but in certain cases they are used in combination with them. The adverse effects of calcium channel blockers include increased pulse rate, flushing and swelling of the ankles, shortness of breath and constipation.
Anti-hypertensive drugs
Diuretics, ACE inhibitors, beta-blockers and calcium blockers are all used to lower blood pressure. In addition, there is a wide range of other drugs which may be used to control blood pressure.
Anti-arrhythmic drugs
Occasionally these are used to control an irregular pulse.
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