Categorized under Gastrointestinal

Imodium (Loperamide)

Imodium (Loperamide)


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Imodium (Loperamide)
DIGESTION: SPLEEN
The spleen lies at the left upper part of the abdomen, touching the stomach, and protected by the lower ribs. It is said to enlarge slightly after meals, and that is the only evidence that it has any connection with digestion. Since the portal vein is presumably extra busy at that time, one might see here an analogy to the five o’clock traffic congestion in our civic centers. At any rate the physiologists have determined that the spleen disposes of old, worn-out, or diseased red blood cells. It leaves the good, healthy cells alone. The tremendous spleens of sufferers from chronic malaria, in which disease the cells are filled with parasites, is a striking demonstration of this. Secondly, the spleen is a reservoir for red blood cells. The discovery of this fact is another example of serendipity, which is so common in medicine: the search for something of value, resulting in the finding of something else of even more worth.
Some physiologists had gone to the Andes to study mountain sickness, which occurs when the blood has difficulty in getting enough oxygen out of the thin air on the mountain heights. It makes no difference except to those whose love of adventure takes them to the Himalayas or to jobs with copper mining companies which carry them up the high Andes. But these investigators found that high altitudes increased the number of red cells in the blood. (Exercise does the same.) These demand more oxygen, and the more red blood cells that are circulating, the more oxygen is delivered. Following this up, they found that the spleen stores blood and lets it out into the general circulation as it is needed. Thirdly, some white blood cells are manufactured in the spleen.
So the spleen is a valuable organ but we certainly do not need it for digestion. Every little while a bad accident ruptures the spleen and, as it is a vascular (that is, bloody) organ, it is necessary to operate and remove it. Having once got over the operation, such patients do not miss their spleens at all.
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