Diamicron Mr (Gliclazide)

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HEART AND BLOOD VESSELS IN DIABETES
Large blood vessels can be damaged in diabetes and this is called macroangiopathy (macro – large, angiopathy – blood vessel abnormality). Macroangiopathy is atherosclerosis, or hardening of large arteries. It is more common in diabetics than non-diabetics. Hard deposits of fatty tissue in the lining of the blood vessel obstruct and eventually block blood flow, or encourage blood clots to form on their roughened surfaces.
Intermittent claudication and angina
Atherosclerosis may cause poor circulation in the legs, producing a cramp-like pain in the calves on walking, which is relieved by rest. This causes intermittent limping -the medical term is intermittent claudication. If you suffer from this, check your feet daily so that small rubs or injuries can be treated immediately: poor circulation leads to poor healing. Do not let your feet get cold in winter; even in a temperate climate it is possible to get frostbite in winter if you have poor circulation.
Atherosclerosis in the coronary arteries which supply the heart muscle may produce chest pain. This is because the muscle is not getting enough oxygen. This chest pain sometimes spreads down the left arm, and it is felt during exercise. It is called angina. If the blood supply to a particular area of heart muscle is completely blocked off, that muscle is damaged and a heart attack, or myocardial infarct, results.
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