Archive for the “Anti-Infectives” Category

March 3, 2010 Categorized under Anti-Infectives

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Other names: Virest
Zovirax (Acyclovir)
QUESTIONS ABOUT SUPPLEMENTS AND DRUGS FOR SPORTSMEN
I’m a swimmer. I wash my hair every time I get out of the pool because I know chlorine can damage it, but the condition of my hair seems to be getting worse. Have you any nutritional suggestions that could help?
Quite a few. Meanwhile, check the ingredients on the shampoos you’re using and make sure they contain no petrochemicals, such as propylparaben (which is much like chlorine and can dry out hair), methylparaben, triethanolamine, propylene glycol or sodium lauryl sulphate. You want a shampoo without added synthetics. There are several on the market designed especially for swimmers. Check with your pharmacist or ask at your local health supply store.
What’s your feeling about the anabolic drugs that have recently been prescribed for athletes?
I’m not in favour of any drugs unless they’re prescribed for specific medical reasons. HGH (human growth hormone) can definitely help athletic performance because of its anabolic (muscle-building) action, but the pituitary gland can be stimulated to produce its own HGH with natural supplements.
The drugs being marketed now have approval only for long-term treatment of dwarfism in children with a specific hormone deficiency. Besides, all the side effects of these drugs are still not known, though high blood pressure, acne, swollen nipples, and symptoms similar to diabetes have already been noted. I’d recommend avoiding these anabolics, at least until more is known about their contraindications.
As a runner, I perspire heavily. Does this mean I should increase the salt in my diet or should I take salt supplements?
Neither! The average American eats at least sixty times the salt required by the body. Additionally, salt tablets have a dehydrating effect. They can cause cramping, gastrointestinal upsets, and can be a contributing factor to heat stroke. Your body knows how to conserve needed salt. In rare cases where there is a salt deficiency, the salt – a pinch – should be mixed in a solution of drinking water and sipped slowly.
I’m a semiprofessional tennis player, and, I believe, nutritionally fit. Nonetheless, I’d like to know if there are any supplements now available that I might not be aware of that could improve my game.
I’d say bee pollen. It’s one of the most energizing supplements for competitive sports players, and an excellent source of vitamins (all of the complex), minerals, protein, and natural gonadotropic and steroid hormone substances. It essentially balances your metabolism, increasing your endurance, and allows you to employ your skills to their maximum potential.
Last week at the gym I heard some of the guys talking about something called DMG. IS it a new drug? What does it do? And is it safe?
It’s not new and it’s not a drug. It can increase oxygen utilization for runners and reduce cramp-causing lactic acid buildup in muscles during exercise – and it’s safe.
Actually, DMG (dimethylglycine) is the active constituent in pangamic acid and is essentially what was formerly known as vitamin 13. Manufactured in our bodies from choline, it’s used with other compounds in the production of hormones, enzymes, and nucleic acids essential for cell growth and repair. It works best when taken in conjunction with vitamins A and E.
*42/137/5*

March 3, 2010 Categorized under Anti-Infectives

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FITNESS POINTS TO FOLLOW FOR LONG AND HEALTHY LIFE
Ask “How Much Exercise Should I Do?”
At first, do very little-not even enough to make you breathe hard. If you have been inactive all your life, a sudden burst of activity could prove dangerous. You might take a medically supervised stress test. Your doctor will put you on a treadmill or a stationary bicycle and monitor your heart, blood pressure, and breathing as you move faster. At the end of the test, an exercise prescription can be written just for you and your needs.
Usually, exercising healthfully requires you to keep your heart beating at a specific level during your workout. You can calculate the pulse rate that’s right for you this way: Subtract your age from 225. Multiply the result by 0.6. If you are 45 years old, it works out like this:
225-45 = 180
0.6×180 = 108= your training pulse (heartbeats per minute)
At this level of exercise, you should be able to talk without breathlessness and shouldn’t feel that the exercise is too hard. As your body becomes conditioned to this level, you’ll be able to increase the load so that your heart will beat faster without discomfort.
Eventually, your heart will beat slowly even under heavy loads. It will recover easily from exertion and go quickly to its resting rate. As a result, that resting rhythm itself will drop.
To get the full training effect, you have to exercise aerobically for at least 20 minutes three times a week. You will find that, by exercising more often and for longer periods, your heart’s capacity to handle exertion will increase all the sooner. But to start, take care to stay within your comfort zone. When you begin weight training, for example, lift only as much weight for as many repetitions as you are perfectly comfortable. Don’t worry; in time, you will be lifting much more-and more easily.
Michael Pollock, director of the Center for Exercise Science at the University of Florida’s College of Medicine in Gainesville, has a 45- to 80-minute training program. It includes warm-up, stretching, moving, 10 minutes; muscular conditioning, 10 to 20 minutes; aerobics, 20 to 40 minutes; and cool-down (stretching, walking), 5 to 10 minutes.
Choose the Time and Place
Most experts favor mornings, before your workday begins. Once you’re in the habit, you will enjoy it. Fresh from a night’s sleep, you’re ready for a workout. Find an exercise place that you can get to easily. Working out at home with your own equipment is fine – once the exercise habit is in place. Millions have been spent on exercise equipment for the home, and much of it gathers dust.
Get a Coach or a Buddy
“A coach has the expertise to guide you mentally and physically,” says Michael O’Shea. In fact, studies by John Martin, a psychologist at San Diego State University, revealed that a good trainer plus a few interest-enhancing techniques can double attendance in an exercise class.
If you can afford one, hire a private trainer. “If you exercise alone,” Mr. O’Shea notes, “everything has to come from within. It is very easy to find excuses not to go to the gym.” The next best thing to a trainer is a buddy who works out with you.
*27/266/5*

March 3, 2010 Categorized under Anti-Infectives

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IMMUNE SYSTEM AND VITAMIN E
Vitamin E (d-alpha-tocopherol) is a powerful antioxidant and has been the subject of much research. Back in the 1950s, Drs W. and E. Shute of Canada first published papers on the use of vitamin E in the treatment of cardiovascular disease. Recent studies have given further credence to their findings and a recent case controlled study published in the Lancet which involved 110 cases suffering from angina and 394 controls, showed an inverse correlation between vitamin E intake and the risk of suffering angina.
Several medical uses of vitamin E have been developed based on an increased understanding of the damaging effects of free radical induced events in tissues. Oxidant species, especially those produced by lipid peroxidation, appear to contribute to the etiology and pathology of chronic diseases including cataract, cardiovascular disease, emphysema, reperfusion injury, and rheumatoid arthritis, as well as cancer. As the body’s principal lipid-soluble antioxidant, vitamin E may play an important role in the amelioration and treatment of these and other disorders.
It appears that antioxidant supplementation slows down the oxidation of low density lipoprotein (LDL) which has a direct effect on atherosclerosis.
The results we have gained in the treatment of many viral and virus related illnesses have been extremely good. The most common would be patients presenting with influenza or common colds, and although full double-blind trials have not been carried out, our patient trials have demonstrated dramatic improvement in all symptoms of these viral infections when taking this combination.
I have also used this combination of herbs and nutrients when treating patients suffering from post-viral syndrome and those who are constantly contracting viral infections. The results of these studies have shown a marked improvement in the patients’ resistance to infection.
I believe it is the combination of the anti-viral properties of echinacea and garlic, combined with the immune stimulating properties of the antioxidants, that enables us to successfully manage viral infections. Also, with the new positive research concerning antioxidants and their role in the prevention of disease, including cancer and heart disease, they are a must for inclusion in preventative medicine.
*41/199/5*

March 3, 2010 Categorized under Anti-Infectives, HIV

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WHEN FIRST DIAGNOSED: UNDERSTANDING AND COMMUNICATING ABOUT
HIV-WHAT YOU NEED TO KNOW: WHAT’S AT STAKE IN BECOMING PREGNANT
Women who have HIV and then become pregnant can transmit this virus to their babies. Women who become infected with HIV while they are pregnant can also transmit the virus to their babies. The risk of transmission is around 30 percent to 35 percent, meaning that about one-third of the babies born to mothers with HIV will also have the virus.
A woman who becomes infected with HIV after she has had a baby has less to worry about. Any woman with HIV infection, regardless of when she became infected, must not breast-feed her baby.
HIV infection is .different in children than in adults. Because researchers have been reluctant to do clinical trials (drug studies) with children, physicians know less about treating children. And in children, the disease progresses more rapidly. Most children with HIV infection will have medical problems by age four or five years, although rare children with HIV remain well until they reach eight, nine, or ten years of age.
Because the chances of transmitting HIV to a fetus are high, and because children with HIV have little hope of cure, women with HIV are usually advised to avoid pregnancy. They are counseled to use effective methods of birth control: not only condoms, but also additional kinds of contraception, like the pill. The same applies to women who are having sex with infected men. Nonsafe sex with an infected man can make you pregnant and can expose you to the virus at the same time. The pill will help prevent pregnancy, but will not prevent the transmission of HIV. Condoms are not as fail-safe as the pill for preventing pregnancy, but are a pretty good barrier to the transmission of HIV.
For women who are already pregnant, the consequences of delivering the baby and the option of abortion should be thought out carefully. Women with HIV infection often say that since the chances that the baby will not be infected with HIV are 65 percent or better, they should not consider abortion. But even a healthy baby can be devastated by HIV infection if the mother or father or brother or sister is infected. You must think carefully about who will care for your baby if your own health should worsen. These things are best considered during the first three months of pregnancy; if you want an abortion, this is the time when abortion is safest.
If a woman has already given birth without prior testing and subsequently learns she has HIV, she should have all her children of preschool age tested. Older children who have remained healthy and developed normally are unlikely to have HIV infection, but some mothers will still want the reassurance of a negative blood test.
*11/191/2*

March 3, 2010 Categorized under Anti-Infectives

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EXAMINATION OF LUNGS: STETHOSCOPE
The art of examining the lungs has been used as long as there has been any real medicine and in recent years it has come pretty close to being a science. Until the last half century or so the only good methods that we had were percussion and auscultation. These are perfectly good Webster’s dictionary words, meaning striking and listening. Like the players of pianos, drums, and cymbals, we strike to produce a sound. Like persons striking partially filled barrels or carpenters pounding on plaster walls to locate concealed beams, we judge from the pitch produced whether we are striking over air or fluid or solid material. In pleurisy there may be fluid in the chest cavity. With pneumonia the affected part of the lung may become solid as liver, so we speak of the condition as hepatization.
The stethoscope
We share percussion with the symphony orchestras. The word auscultation we have almost entirely ursurped, thanks to the brilliancy of a most poetically named member of our profession. Many a person with a humdrum name has wished for a more picturesque one and not a few have helped themselves to better. A century and a half ago a French family bestowed upon their fortunate son the exquisite title of Rene-Theophile-Hyacinthe-Laennec. So far as I know he was never, despite this, a poet, but he was a great helper in the science of medicine. Several important diseased conditions were first described by him, but his great contribution was a new method of determining the faint sounds produced within the chest. He invented the stethoscope.
When a cartoonist wishes to picture a physician, he equips him with either a head mirror or a stethoscope. As a matter of fact, the former is pretty awkward for us who are not nose and throat specialists. But we all use stethoscopes. The principle is simple. Hearing is the effect produced on the ear by air waves from a vibrating object. It has long been realized that these waves can be directed or steered. For instance, in St. Paul’s Cathedral in London, one can whisper gently against the inside wall of the dome and the sound will be heard by a person holding the ear to the opposite wall a long distance away.
While Laennec was out walking one day, he saw some children playing about a long pipe lying upon the ground. The child at one end would whisper gently and the one at the other end could hear clearly. It occurred to Laennec that the scheme might work in listening to chests so he went home, rolled a piece of paper into a cylinder, one end of which he placed against his patient’s chest. It worked. He then made a hollow wooden tube. Now we have elaborate instruments with well-fitting ear pieces, flexible rubber tubing, and a bell or vibrating disk at the other end.
This is still a valuable machine despite the jokes that doctors make about it and their fellow medical men who use it. The Mayo brothers used to say that their doctors carried stomach tubes hung around their necks instead of stethoscopes. I have been told that Dr. Merrill C, Sosman, of the Peter Bent Brig-ham Hospital in Boston, who knows that his X-ray will show some fine changes in the lungs that cannot be located by a stethoscope, has a framed stethoscope, on the wall of his office, labeled: “Obsolete instrument formerly much used by internists.” But the internist cannot carry an X-ray machine hanging about his neck. He can quickly learn a lot with Rene Hyacinthe’s handy little gadget. Later he may supplement this with the X-ray.
Some of you may remember using crystal radio sets. To my mind, what you did hear over them had a clearer, more perfect note than what you often hear over expensive modern machines. Old-time medical practitioners thus compared the naked ear and the stethoscope. In our town, about the time when I commenced practice, there was a highly esteemed, elderly physician who when the stethoscope sounds did not quite satisfy him, would put his ear directly on the patient’s chest. One evening, after an unusually tiring day, he got an emergency call. Reluctantly he took his bag and trudged off, as he knew that his horse was also tired. The patient was a delicate young lady with a cough. With his stethoscope he listened long and carefully to her chest, but could not satisfy himself as to what he heard. Telling the maiden of the occasional advantage of listening with the naked ear, he abandoned his scope, placed his head upon her breast and again listened long and carefully. The patient finally became more and more restless, until, glancing down she saw that the old gentleman was sound asleep. So, put your calls in early, if you can. Don’t overwork a willing horse – or a willing doctor.
*25/276/5*

March 3, 2010 Categorized under Anti-Infectives

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FITNESS TO STAY HEALTHY: SOME POINTS TO FOLLOW
Make the Decision
Before you read further, follow these instructions from Dr. Rod K. Dishman, director of the Behavioral Fitness Laboratory at the University of Georgia in Athens. To allay fears that you’ll look foolish while exercising and get only small returns for your time and effort, he suggests you fold a sheet of paper down the middle and write the pros for exercising on one side of the fold and the cons on the other. Try it.
Now look at your negatives. Did you put down “not enough time”? Are you so busy that you can’t spare an hour or two a week? Often, in the morning, I met David Rockefeller, the financier and philanthropist, at my exercise club in New York. And I thought, “If he can find the time to work out, I surely can.”
Examine each pro and con fully. At the end, write “I will exercise” or “I will not exercise.” If you vote no, you can stop reading now.
Pick the Exercise
First, the workout has to be enjoyable and healthful, so choose exercises that are both effective and fun. They fall into three categories:
1. Aerobic: makes your heart go fast and your chest heave, benefits your heart and lungs, and fights fatigue and depression 2. Muscle-strengthening: helps in sports, facing emergencies, avoiding accidents
3. Flexibility: eases joint movement and muscle stretching, relieves the pains of arthritis, and helps avoid the cramps and cricks that come with the moving of weak muscles
There’s a simple way – change your style. Instead of taking elevators, climb the stairs. Instead of driving, walk – at least the shorter distances. Or park your car halfway and walk the rest, but stride at a brisk pace. On weekends, get lively: Try roller-skating, swimming, cycling, or taking long, zippy walks.
Leonard Epstein, professor of psychiatry at the University Of Pittsburgh School Of Medicine, found that for children such changes work far better than formal programs. Both are equally effective in helping children lose weight, but the children who make activity part of their lives keep the weight off and keep on exercising. It could work for you.
*26/266/5*

March 3, 2010 Categorized under Anti-Infectives

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X-RAY FOR LUNGS EXAMINATION
The stethoscope is still the constant companion of the internist, but we have other methods that undoubtedly go beyond it. I think that every medical man will agree that the chief of these is the X-ray. I trust that all of you know that it does not “take pictures” but throws shadows on a plate or film. Substances vary in the amount of shadow they cast. The rays go unimpeded through air. The heavy heart muscle throws a deep shadow, and a lead slug in the lungs would let no rays through. There are all gradations, and the skill of the roentgenologist now seems marvelous to us whose accomplishments are more highly developed along other lines. Not only are the shadows of the tissues studied by X-rays but “contrast media” are also used. These are substances which show heavy shadows when they are introduced into the body. They are probably more familiar to you when used to outline the stomach, intestines, gall bladder, kidneys, and even the blood vessels. They are introduced into the lungs by spraying them down the windpipe and they are then breathed into the deep recesses. If the bronchi are misshapen, plugged or end in large dilations, the outlines will be shown on the X-ray films. After giving all these commendations to X-rays, I feel it only fair to say that an X-ray friend today told me that the man with the stethoscope and the percussing finger can study certain things better than he and his X-ray machine.
*26/276/5*

March 3, 2010 Categorized under Anti-Infectives

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STAYING HEALTHY: START EXERCISING ? AND STICK WITH IT
Exercising is a lot like dieting. You know that losing weight and getting in shape is good for you. You’ve started a diet or an exercise program a dozen times. But, after a few weeks or months, you’re sitting in front of the TV, munching corn chips and feeling guilty about not doing pushups or swimming or something.
Maybe one in three of us who starts exercising sticks with it for a year. The Centers for Disease Control in Atlanta report that only 10 percent of Americans exercise enough to reap important health benefits. Of those who need it most-the overweight, those with high blood pressure, and heart-attack convalescents-far too few will start, let alone stay with, an exercise program.
At last, scientists are uncovering the secrets of how to start working out and keep on doing it-for life. Parade can now offer you some of the best of the known techniques for making exercise into an enjoyable, lifesaving habit.
“If you want to live longer, exercise. It’s that simple,” says Dr. Ralph Paffenbarger, Jr., professor of epidemiology at the Stanford University School of Medicine in California. He studied 17,000 Harvard graduates and found that those who exercised more really did live longer. Perhaps best of all, if you follow a good exercise program, you’ll look and feel 10 to 20 years younger.
However inactive they were in the past, almost everybody can exercise an hour or two a week and easily avoid injuries. Your own customized exercise program need not interfere with work or family life and might even enhance them.
Michael O’Shea, Parade’s fitness editor, has run successful training programs for years. “I’ve rarely seen anybody who couldn’t do some sort of physical activity if he or she got the right exercise in the right way,” he says.
So why do most people avoid exercise at all costs? Generally, because the workout is uncomfortable. Many trainers will say, “No pain, no gain.” In this case, the reverse is true: Pain is punishment. And psychologists have proved that habit formation relies on reward.
*25/266/5*

March 3, 2010 Categorized under Anti-Infectives

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STAYING HEALTHY: SUGAR IN YOUR DIET
Scientists have had a hard time killing the myth that sugar turns calm children into fidgety, talky, aggressive terrors. But a number of careful tests have failed to find sugar-triggered hyperactivity. Dr. Markus Kruesi, a child psychiatrist at the National Institute of Mental Health in Bethesda, Maryland, checked 29 children for hyperactivity after sugary meals. Parents of some of the children had reported that sugar turned the kids into jittery robots. “We just did not find it,” says Dr. Kruesi. “Not a single child.”
People with diabetes need to control the amount of sugar they eat because their bodies lack insulin to burn up sugar. And the high blood-glucose levels can lead to serious problems. But in no way does sugar cause diabetes. Another myth states that if you take in a lot of sugar at a meal, your body rapidly burns up or stores that sugar, and you are left with too little in the blood. That’s called hypoglycemia. In the 1970s, it was blamed for everything from the tyranny of bosses to Monday-morning blues to cancer. But, except for people with diabetes, a rare few suffer from hypoglycemia.
Nor can you especially blame sugar for putting on pounds. In fact, it turns out that most of the calories in sweet foods come from fat. Sugar plays a part by making the fatty foods?cake, candy, pie, ice cream?tasty.
The Sugars Task Force systematically reviewed all the diseases with alleged sugar causes. High blood pressure? No. Atherosclerosis and heart disease? No. Cancer? No. Gallstones? No. Blocks vitamin and mineral absorption? No.
Some consumer groups contend, however, that many children’s cereals have much more sugar than fiber and that Americans in general eat far more sugar than the task force reports, killing their appetite for the good foods and rotting their teeth. But that’s all just supposition, the task force says.
In short, there are no major bad effects from the amount of sugar that most Americans eat today.
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March 3, 2010 Categorized under Anti-Infectives

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LUNG DISEASES: PNEUMONIA
Pneumonia is the accepted name for pneumonitis, or inflammation of the lungs. Every textbook article starts by telling us that Hippocrates was familiar with it. Yet from his day until the last decade or so little was added to our knowledge of it except a lot of technical details of interest only to trained students of disease. As a matter of fact, I have just read the latest, highly esteemed textbook of medicine and also Sir William Osier’s Practice of Medicine, written a half century ago; that is, I have read their articles on pneumonia. In my estimation Osier had far the better story except that he was just too early for X-ray examinations, and as for treatment, he could say only this: “Pneumonia is a self-limited disease which can neither be aborted nor cut short by any known means at our command.”
John Bunyan, in his Pilgrim’s Progress, spoke of consumption as “Captain of the Men of Death,” and over two centuries later Osier decided that pneumonia then merited the name. It was a little difficult to say just how important it was as a fatal scourge, for many a long drawn-out chronic disease was finally mercifully ended by an acute attack of pneumonia, when the patient had become too weak to aerate the lungs and keep them healthy. For this reason Osier called it “The Friend of the Aged.”
It is agreed that pneumonia is caused by infective organisms, of which the most common is the pneumococcus, but numerous others are found guilty at times and some of them are especially wicked. In the great, widespread influenza epidemic towards the end of World War I, people were dying like flies, often it would seem, of streptococcus pneumonia. Nowadays we hear much of a particularly miserable virus pneumonia.
The pneumococcus is not a scarce organism; it can be found in many places in the body, especially in the nose and throat secretions, but it does not at all follow that the patient is sick. It would seem that the germ lurks about, and when it finds conditions just to its liking, it seizes the victim. Neither does it follow that the patient has to be weak, puny, or ailing to succumb. Husky young athletes, apparently in the pink of condition, may be struck down. Cold has always been regarded as a cause but Montreal is a very cold city in winter and Osier reported that in January, the coldest month of the year, there was a comparatively low death rate from pneumonia. In the late winter and early spring of 1917 a thousand wounded might be admitted to our big hospital in a night. I wore all the clothes that I could pile on me and felt congealed. Yet the wounded boys were not very warmly clad, particularly the Scotch with their bare thighs, and they had been exposed to cold and wet for long, long periods. If cold and exposure were great factors in pneumonia, there should have been epidemics then, but there were none.
There was one aspect of the pneumonia of the old days that was a great source of elation to the physician and family and yet it was also at times a frustration to the former. This was the spectacular “crisis.” Many diseases, typhoid for instance, get well very slowly and gradually. Not so with the characteristic recovery of pneumonia. The patient might appear desperately sick, with high fever and prostration. Then, usually in five to twelve hours, but often in an hour, the fever would drop many degrees, the respiration return almost to normal, the pulse would slow, and the patient would pass from a state of extreme hazard and distress to one of safety and comfort. There was a belief among physicians that these crises occurred on the odd days, as the third, fifth, or seventh.
Now why should there have been any frustration about such a delightful phenomenon? The best physicians have always been chary about using the word “cure.” As they knew that there was no good treatment for pneumonia, they relied only on good care. My friend, Dr. Frank Fulton, as he was making morning rounds with the intern, was shown a man, exceedingly sick with pneumonia. He studied him carefully and then resignedly remarked, “Well, the best thing we can do for him is to put him to bed with a good nurse.” But in the minds of many people there is always a cure. The question is where to find it. A family may be told by a kind neighbor of a similar case miraculously cured by a cultist. The family, in desperation, might then dismiss the doctor and call in the wonder worker. If the crisis occurred a day or so later, could that family ever be convinced that the sick man did not owe his life to their wisdom in switching? They could not.
All that, however, is ancient medical history. The sulfa drugs came along in the 1930′s and made life hard for a lot of pathogenic bacteria. That is what we call those which attack our health. (The others, most of which are trying to help us, are called saprophytic.) Then came Armageddon, just before the Second World War, and penicillin has made pneumonia a weak warrior. Do not think, though, that it is completely out of the picture. The forces of evil never give up the battle and organisms other than the pneumococcus are still bitterly attacking the lungs.
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March 3, 2010 Categorized under Anti-Infectives

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COPING WITH INFECTIONS: WHOOPING COUGH
Grown up as you are, you may even have whooping cough. This is one of the diseases which, like shingles, is often referred to in a joking way and yet actually is very far from a joke. It is in most cases a childhood disease for it is so contagious that few children escape it. The Bordet-Gengou bacillus, named after the scientists who identified it, has been definitely incriminated. The scientific name for the disease is pertussis, which after all is just Latin for a bad cough.
Newborn babies seem to have immunity against a good many infections, but not to whooping cough. It is most common between four and eight years of age. Because in its early stages it appears like any cough, and thanks to the prevalence of head colds, laryngitis, and bronchitis, nearly everybody has a cough in the spring and early summer, the disease is not recognized until it has been passed freely around. Hence epidemics.
When the infection is well developed there is a sticky, thick secretion in the windpipe and its branches in the lungs. This irritates and tickles so that children go into paroxysms of severe coughing so steadily that they cannot get their breath. Finally when they are blue in the face with choking, they draw in a deep breath with such force that it causes the characteristic sound of the whoop. Frequently this will loosen a great deal of the secretion, which while being coughed up often results in gagging and vomiting. There may be a few weeks of these procedures. The vomiting and accompanying starvation may cause the loss of a lot of the fluids and salts of the body, with a condition which physicians call alkalosis but which the public, aided by patent medicine advertisements, are much more apt to call acidosis.
The younger the patient, the more serious the disease. Broncho-pneumonia is often associated with it and is the gravest danger. Therefore pediatricians give whooping cough vaccine as a preventative very early in life. Certainly do not expose untreated youngsters to the disease if it can be helped.
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March 3, 2010 Categorized under Anti-Infectives

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HEALTHY DIET: ONE LUMP OR TWO?
To hear some folks talk, you’d think that refined sugar caused or contributed to nearly every known disease. The actual list includes cancer, diabetes, low blood sugar, heart disease, high blood pressure, hyperactivity in children, rotten teeth, gallstones, obesity, and hyper-cholesterol. From scientists both in and out of government, the verdict: In the amount currently consumed, sugar is safe for almost everybody. It triggers no major disease, makes few if any people fat, and it doesn’t make kids climb walls. It does contribute to tooth decay, but no more than other foods.
The worst you can say about sugar is that it is pure calories, devoid of any other nutritive value-”empty funcalories,” nutritionists call them, meaning that if you eat too much sugar, you cut down on nutritious food and leave yourself undernourished by an unbalanced diet.
“Most people will use sugar reasonably in amounts that don’t drive out good food,” says Dr. Walter H. Glinsmann, who headed a special Sugars Task Force for the Food and Drug Administration. His group wiped out almost all of the indictments against sugar.
Still, nutrition experts worry about teenagers, who may consume up to eight sugar-sweetened soft drinks a day, or 1,200 calories out of the 2,500 an active young person will eat. That doesn’t leave much room for vegetables, fruits, cereals, beans, meats, and dairy products-all essential to a well-balanced diet.
The American Dietetic Association (ADA), which speaks for most nutritionists, says it’s OK to eat sugar in a well-balanced diet. Too much sugar, the ADA agrees, does interfere with getting the good foods.
How much is the right amount? It varies from person to person, but the ADA suggests that you’re safe from an unbalanced diet if you eat no more than 15 percent of your calories in sugar. If you consume 2,500 calories a day, take only 375 calories in sugar-about the amount in two soft drinks. But keep in mind that you’ll get added sugar in other foods you eat, such as breakfast cereals, breads, canned goods, frozen dinners, and desserts. Now food manufacturers often tell you clearly how much sugar there is inside.
The bad effect of sugar on the teeth is real. The bacteria in your mouth turn the sugar into acid, which dissolves the dental enamel. However, the latest research blames the number of times you eat rather than specifically what you eat. “If you eat cookies, bread, potato chips, raisins, apples, bananas, milk, soda-it’s all the same,” says Dr. Stephen Moss, chairman of the department of pediatric dentistry at New York University College of Dentistry. “Every snack starts the bacteria working again. Limit kids to snacking only two or three times a day.”
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March 3, 2010 Categorized under Anti-Infectives

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TROUBLES OF RESPIRATORY TRACT: COMMON COLD
The Britishers, who go doggedly at things, have been conducting a tremendous research on a windswept hilltop just outside Salisbury in southern England. This may sound foolish to you who know how you catch your colds and have learned from advertising campaigns how to cure them, but, although almost everyone has his own foolproof technique for preventing or curing colds, yet colds are as numerous and as troublesome as ever. The Salisbury investigators have experimented with over fifteen hundred volunteers. They pay the traveling expenses, give free board and lodging and a little pocket money. In this way they get an intelligent, cooperative group, mostly university students. The last I knew, the project had been going on for several years, and the experimenters still believed that colds are caused by a virus or viruses.
These human guinea pigs are carefully isolated for four days to make sure they are not developing colds, which usually occur in from two to three days after exposure. Then they have material placed in their noses. This may be simple broth, egg white, or what have you. In no case does the patient or observer know what has been used. Then many careful observations are made. About 60 per cent of those who actually get infected material respond with colds.
The British scientists think that catching a cold in real life depends on receiving quite a small dose of virus at a time when one’s defenses are momentarily off guard. If this were not so, we would always be having colds, for one of their experiments was putting fluorescein the nose of a patient with coryza (dictionary name for a common cold). The most minute amount of this can be seen under ultraviolet light and they found it everywhere the patient had been: on hands, face, all over the room, even on the food. Now won’t you, please, when you have a cold, stay at home, and not spread your contamination all over town.
One experiment tried at Salisbury was to chill the subjects thoroughly. The latter were soaked in hot baths and then stood about undried in a cold passage as long as they could stand it. In addition the poor unfortunates wore wet socks for some hours. Chilling alone produced no colds. I knew it wouldn’t. I have tried the same experiment on myself thousands of times.
However, chilling plus the virus produced more colds than the virus alone in people kept warm and comfortable. That is what was found at first, and this agrees with the preconceived ideas of everybody. The bane of investigators is preconceived ideas. These people avoided them and as they said, “We were foolish enough to repeat the experiment.” This time, those with the virus alone had twice as many colds as those with the virus plus chilling. There is no good evidence that chilling is the wicked thing that you all think it is.
I realize that there is little in the above that is really believed by run-of-the-mill people, including most of my doctor friends. But this is the first experiment, carried out on a large scale of such a careful nature, that I know of. To my mind it shows that the only factor of importance is infection. Eliminate that and “colds” will not amount to much.
One thing that is particularly disturbing to people with colds is the extra secretion of “mucus.” This is a well-known word. I think you all use it glibly and you mean by it a very disagreeable substance. However, in discussing the digestive system, I mentioned that there is a secretion of mucus all along its extent, and at the upper portion the digestive tract and the respiratory tract are one and the same. This mucus, put there to lubricate and protect, naturally responds to emergency calls, and colds undoubtedly furnish most of these emergencies. Then we get an over-secretion of mucus. The body can’t always regulate furnishing just enough and not too much. The mucus secretion that goes with a cold is a nuisance, but you have got to be philosophical about it. The body’s intention is a right one.
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March 3, 2010 Categorized under Anti-Infectives

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BULIMIA: WHEN STAYING THIN IS A THICKNESS
You may be bulimic and hide it from yourself. Here are some of the signs:
1. Eating huge amounts of food
2. Vomiting or using laxatives to purge
3. Hiding your binges from others
4. Trying to control your weight by binging and purging
5. Feeling out of control once you start eating
Bulimics may maintain normal body weight and look healthy, but they are prone to such ailments as swollen salivary glands, an inflamed pancreas, and gallbladder problems. Constant vomiting harms the stomach and food pipe, or esophagus. Stomach acid coming up into the mouth erodes tooth enamel. I saw a bulimic with so much enamel gone; only tiny stubs of teeth remained.
At its worst, bulimia can kill. Purging empties the body of potassium; this makes the heart irritable and prone to stop. The estimated death rate for severe bulimics is 1 to 10 percent.
Some bulimics spend up to 300 dollars on food. They isolate themselves at work and at home, even from their spouses. Sometimes they cannot work and lose their jobs.
Bulimia is related to anorexia nervosa, a condition in which patients refuse to eat anything at all and waste away.
Dr. C. Philip Wilson, Columbia University’s College of Physicians and Surgeons in New York City, calls anorexia nervosa and bulimia two sides of the same coin because both are rooted in the fear of becoming fat. Every bulimic I spoke to confessed that fear.
Nobody knows why the binge-purge syndrome snares mostly women. Dr. Pope and Dr. James I. Hudson, also of McLean Hospital, call bulimia a form of a major depressive disorder. Says Dr. Pope, “Among our bulimic patients, 80 percent suffer from major depression or manic depressive illness.”
Dr. B. Timothy Walsh, of Columbia University’s College of Physicians and Surgeons, reports success with antidepressant drugs. “Bulimics not only stop binging and purging,” he says. “For the first time, they feel better.”
One of Dr. Pope’s patients, Sheri Swanson, bulimic since she was 18, says she hid the problem from everyone: “It’s so shameful.” All treatments failed until Dr. Pope prescribed an antidepressant drug, desipramine. Sheri noticed a difference right away. She says, “This oppressive cloud was lifted. Within a matter of weeks, the binging was gone. It was astonishing.”
Studies also show that bulimic women have other psychological disturbances. Up to a third have attempted suicide. Bulimics tend to abuse alcohol and street drugs. “We think a third of our patient have kleptomania too,” says Dr. Pope. “Imagine a middle-class woman who can buy anything she wants yet steals a bottle of perfume.”
Treatment for bulimia varies. Daniel Baker, Ph.D., director of the eating disorder program at University Hospital of the University of Nebraska Medical Center, Omaha, trains bulimics to turn away from food and build self-esteem.
Associates for Bulimia and Related Disorders, a group of psychologists in New York City, teaches clients to turn to other people rather than to food. Says Ellen Schor, Ph.D., a co-director, “We tell them, ‘You have a food addiction. Food has been your secret lover, your confidant, and worst enemy. If you go on like this, you will never get close to people.’” In groups, patients are taught the facts about bulimia, urged to keep diaries and to make contracts with themselves to change. Co-director Judith Brisman, Ph.D., reports that after a year, a third of the group no longer binged and another third cut their gorging by half.
When all else fails, Dr. Katherine Halmi, of Cornell University Medical College in White Plains, New York, takes a drastic step. She hospitalizes her patients for an average of 3 months. Hospitalization keeps the bulimic away from food; in serious cases, it can save the person’s life. Step by step, patients are taught to eat normally.
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March 3, 2010 Categorized under Anti-Infectives

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RESPIRATORY PROBLEMS: COUGH
The upper respiratory system attempts to get out of our lungs the material that ought to come out. Unfortunately it does not always do a complete job. Then our great ally is a cough. Much as we dislike a cough, it is not wished upon us for our sins. It is intended for our protection. We accomplish it by taking a breath, closing off the top of the windpipe with our muscles and then squeezing hard with our chest muscles and belly. As the top of the windpipe opens suddenly, the air rushes out with an explosion and may carry the offending matter with it.
Cough can be voluntary or involuntary; that is, we can cough when we wish and we often cough because we cannot help it. Most coughs are somewhere in between this. But any cough that persists should be investigated because it is frequently a symptom of serious trouble.
The careful physician can find signs from head to feet which might give insight into the cause of the cough. Some of them might surprise you. A physician friend of mine told of four cases of chronic cough with which he had had experience, all caused by hairs in the ear canal, pressing on the eardrum. This may not at first hand sound reasonable to you but you must know that the heart, lungs, and stomach are controlled largely by the tenth cranial, or vagus, nerve. Branches of this nerve also go to the larynx and eardrum. So if you have trouble in your ear or your vocal cords or have an irritated stomach, any one of these may set you coughing.
It is the irritation of the nerve endings by any of these things that results in coughing, and unfortunately men and women find many things in modern life to irritate them, even though they cannot cough them up. Probably the cigarette cough leads all the others for it goes on continually, while all of us have some respite from the common cold, in which the droppings from the back of the nose are a nuisance. All radio listeners are aware of the outbursts of coughing which come when there is a pause in a symphony concert, for much coughing is just due to nervousness. So buy your cough medicines if you must, but, if the cough persists, you will be smart to try to find out what it is all about.
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March 3, 2010 Categorized under Anti-Infectives

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INFANTS AND SURGERY WITHOUT ANESTHESIA
He looks so helpless, strapped to the tiny operating table. Premature, newborn, weighing less than 2 pounds, the infant has a severe heart malformation. Surrounding him, hunched over, masked doctors and nurses strive desperately to repair what nature forgot to do.
The surgeon’s scalpel cuts through skin and muscle and nerve. The infant emits a muffled cry. He has been given a muscle relaxant but no painkilling drug, no anesthetic. Why?
First, doctors have long argued that premature infants could not feel pain because their nervous systems had not fully formed. Second, confronted with a tiny, sick baby barely clinging to life, surgeons and anesthetists often fear that a pain-killing drug might endanger an already weak breathing system or stop a heart hardly able to beat.
Dr. David Swedlow, assistant professor of anesthesia at Children’s Hospital of Philadelphia, says, “The judgment call is whether you think this child can survive the anesthetic, balanced against whether the child will survive the pain.”
Concerned doctors and nurses estimate that physicians withhold anesthesia in half of all major surgery for prematurely born infants. Every year in this country, 200,000 preemies spend the first weeks, sometimes months, of their lives hospitalized in intensive care units.
But protests were mounting as parents like Jill Lawson of Silver Spring, Maryland, discovered that doctors have kept painkillers from their babies. Mrs. Lawson’s son, Jeffrey, was born in February 1985, 14 weeks premature and weighing less than 2 pounds, suffering from heart and lung problems. He underwent surgery.
“Jeffrey had holes cut on both sides of his neck,” Mrs. Lawson says. “Another hole was cut in his right chest, an incision was made from his breastbone around to his backbone, his ribs were pried apart, and an artery near his heart was tied off. He was totally conscious throughout IV2 hours of surgery.” Jeffrey died 5 weeks later.
When Mrs. Lawson learned that no anesthesia had numbed her child to the pain, she first felt agony, then fury, and, in the end, vowed to change this practice. She wrote letters to medical organizations and government agencies and finally “went public” in a newspaper story.
Doctors have struggled with the problem for years. It was discussed at a 1970 conference of anesthesiologists held in Palm Springs, California. There a doctor stated that preemies did not need anesthesia, just some adhesive tape to hold them down.
Dr. Richard J. Ward, then of the University of Washington School of Medicine in Seattle, was in the audience. He countered that comment angrily, saying, “May I just mention that in no animal laboratory in the world could you get away with anesthetizing a puppy with adhesive tape. Some of us feel that perhaps an infant is worth at least the same amount of care as a puppy.”
Parade has learned that Mrs. Law-son’s efforts and Dr. Ward’s biting comments have not gone unheeded. Through interviews, we found that many, but not all, anesthesiologists now make every effort to ease an infant’s agony.
*12/266/5*

March 3, 2010 Categorized under Anti-Infectives

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CHILDREN?S SURGERY: WITH OR WITHOUT ANESTHESIA?
Dr. Fritz Berry specializes in pediatric anesthesiology at the Children’s Medical Center at the University of Virginia in Charlottesville.
“With new techniques,” says Dr. Berry, “we can anesthetize preemies as we do any patient with an unstable circulatory system. But there are doctors who do not feel secure about giving anesthesia to very sick preemies. Some fear that as soon as they do, these children will die.”
But the opposite may be true: Killing their pain may help these babies live. Dr. K. J. S. Anand, a researcher in the anesthesia department at Children’s Hospital in Boston, studied preemies who needed surgery to repair an artery near the heart.
Doctors gave one group of babies the muscle relaxant curare plus nitrous oxide (laughing gas), a mild anesthetic. The others received fentanyl, which puts the patient to sleep. Dr. Anand found that, following surgery, those given fentanyl had fewer problems with breathing and heart stability. His measurements of blood hormones showed clearly that, without full anesthesia, the babies experienced great stress and pain.
“I assume these babies feel pain,” says Dr. Swedlow, “and we try to give them an anesthetic – as much as we feel they can tolerate. We really have no way of knowing just how much is really safe and effective. It is better to survive and perhaps feel discomfort than die and not feel any discomfort.”
All of this leaves parents in a quandary. Debra Scharg of Oakland, California, an obstetric nurse, gave birth 3 months prematurely to Jacob Eli. He weighed 1 1/2 pounds and had a severe bowel infection. The Schargs say they gave permission to operate on the 18th day of Jacob’s life, on the condition that he be anesthetized. Jacob did not survive the surgery. The Schargs say they later found that medical records showed no evidence of Jacob having received painkillers.
“As it turned out,” Mrs. Scharg says, “our son was much too sick to go through the operation. We wished that the doctors had just let us hold Jacob to say good-bye to him. Instead, he died on the operating table in pain.”
Jill Lawson, determined to help other babies avoid Jeffrey’s fate, urges that parents discuss the issue with their pediatrician and the anesthesiologist, not the surgeon or assistant surgeon. It’s the anesthesiologist who makes the decision to give painkillers.
As of now, no laws compel a doctor to follow the wishes of an infant’s parents. If the doctor feels that anesthesia might impose too great a risk, he can order the drugs withheld. “Doctors need to spend more time talking to the parents,” says Dr. Berry. “We, too, are extremely concerned about the child.”
*13/266/5*

March 3, 2010 Categorized under Anti-Infectives, Antibiotics

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YOUR SPECIAL VITAMIN SHAPE-UP
All exercises make different demands on the body, and the body requires many different nutrients to meet these demands. I have outlined a number of personalized regimens for a variety of specialized exercise needs. I’d advice looking all of them over so if you discover that you fit into more than one category, you can adjust the combined regimens to avoid double-dosing and merely add the necessary additional vitamins.
Before starting any regimen, check with a nutritionally oriented doctor. Please keep in mind that the regimens are not prescriptive nor are they intended as medical advice.
You will notice that in many cases I advise what I call an MVP, a Mindell Vitamin Programme (which can make you an MVP – a Most Valuable Player in the fitness game). This basic vitamin trio is my foundation for nutritional health.
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*33/137/5*

March 3, 2010 Categorized under Anti-Infectives

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BRAIN INJURIES: NEW TECHNIQUES FOR BRIGHTER FUTURE
Brain-injured must be taught new ways to think – the old thought pathways are blocked forever.
Thomas Kay directs research at the Research and Training Center on Head Injury and Stroke at New York University (NYU) Medical Center in Manhattan. He says that the amount of damage can affect a patient’s thinking and emotional changes. A severely injured patient often looks and sounds different, with jerking movements, unclear speech, peculiar gestures, and odd facial expressions.
Yehuda Ben-Yishay directs the head trauma program at NYU’s Rusk Institute for Rehabilitation Medicine. He points out that brain trauma cuts across many intellectual functions. The patient’s attention may wander. He may not coordinate reasoning with action; even if he finds the solution to a problem, he cannot easily carry it out. He cannot formulate goals either at work or in daily life. He may not even be aware he has memory problems.
Dr. Ben-Yishay’s group offers a 20-week program to teach the brain-injured how to think and act. For 5 or more hours a day, the patients solve thinking problems, with both pencil and paper and with computer. Patients also do public speaking?under pressure?so they later can interact with bosses and others without inappropriate behavior. After the training, 63 percent have been able to earn a living.
In 1984, Chris Willner of North Miami Beach, Florida, then an accountant, was driving her car when another hit her broadside. Upon waking up after 2 weeks in a coma, she couldn’t speak, write, or remember things. She walked with a limp.
“Dr. Ben-Yishay’s program gave me a fresh start,” says Mrs. Willner, now working again as a secretary. “I was lost, but they taught me how to remember things and to have more confidence in my abilities. Now I can handle my house, my son. I am pretty darn close to how I was before the accident.”
Research points to some inspiring advances. For example, electric stimulation of sperm ejaculation has enabled paralyzed husbands to become fathers. Women whose sex organs are unaffected by their injuries can have babies normally. Karen Silver Karlin of Huntington, New York, had her neck broken in a car crash in 1979. Later she had a trouble-free pregnancy.
Another exciting development is computer-driven electrical stimulation, given directly to leg and thigh muscles. This treatment enables paraplegics to walk. Dr. E. Byron Marsolais of the Veterans Administration Medical Center in Cleveland has developed a system that lets paralyzed patients walk on flat ground and on stairs.
Dr. Marsolais inserts 48 electrodes under the skin and into muscles. A computer controlled by a hand-held device sends electrical signals into the muscles, forcing them to contract in just the right sequences to produce a walking motion.
The system still needs work to make it operate more smoothly, slim its bulk, design an implantable one, and reduce its cost. More than 100 scientists and engineers have worked on it.
Researchers also stimulate the diaphragm, the large muscle in the abdomen that pumps air in and out of the lungs. They help patients breathe by activating the paralyzed diaphragm to contract. The Food and Drug Administration has approved a device for this function.
Engineers are also working on an electrical stimulator to help patients empty paralyzed bladders.
Biologists are still testing transplants of animal fetal tissue to reestablish the broken nerve connections. Fetal tissue grows rapidly and could help injured nerves before they die.
At the Medical College of Pennsylvania in Philadelphia, scientists partially have healed spinal cord injuries in rats by transplanting nerve tissues from rat fetuses into the spinal cord.
Across the nation, scientists are hard at work trying to make paralyzed bodies respond and to lift the victims from their wheelchairs.
*11/266/5*

March 3, 2010 Categorized under Anti-Allergic/Asthma, Anti-Infectives

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NEW ADVANCES STOPPING A STROKE: CHEMICAL/DRUG RESEARCH
When an artery bursts or is clogged, it can’t supply the brain cells with blood, and they die. The injured and dying cells then emit substances that spread the injury to a widening circle of brain cells. Release of these substances allows the entry of excess calcium into the cells, followed by the entry of water, which bloats and destroys the cells. Chemical compounds to reduce the risk to brain cells during stroke are now being tested for human use. They would protect the cells from being flooded with water in this deadly process.
Brain scientists also are testing many chemicals for their ability to dissolve blood clots and stop a stroke in progress. These include streptokinase, an enzyme from bacteria, and TPA, a chemical found in tiny amounts in human blood. Studies show that they destroy clots in the coronary arteries. There is some proof that these chemicals destroy clots in brain arteries.
An experimental anticoagulant called Ancrod comes from the venom of Malaysian pit vipers. It thins the blood, breaks up clots, and has been tested on about 500 persons with some success.
In addition, researchers are focusing on ways to prevent clot formation. Blood clots in the coronary arteries produce heart attacks. Antiplatelet (blood-thinning) drugs, including aspirin and warfarin, are being tested on a large scale to see which ones help prevent stroke. If you have suffered a stroke, the chances are that you will have another. Treatment with blood thinners can extend the life expectancy of stroke patients.
Aspirin therapy – depending on the patient and the dosage – has been found to stop clotting. If you are 50 or older, researchers urge you to consult with your physician about aspirin therapy to help prevent stroke or heart attack.
Warfarin, a prescription drug for humans, is a blood-thinning chemical. It was long known as an ingredient in rat poison. When used to prevent stroke, it requires careful management, including monthly blood tests and adjustments of the dosage, as its effects vary with age.
*7/266/5*

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