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Other names: Monopril
YOUR HEART: A USER’S GUIDE
If it’s any comfort at all, you’re not alone. Millions of Westerners have one or more forms of heart disease, blood vessel disease, or both. Of these, a percentage have a history of heart attack, angina pectoris, or both. Each year as many as 1.5 million Americans will have a heart attack. So far you’ve been lucky: more than a third of those heart attack victims die. As to treatment, about 350,000 coronary bypass surgeries and almost as many angioplasties are done annually in America.
Amazingly, to me at least, most heart patients know almost nothing about their hearts, how they work, and how they got sick. Many would retort by saying that such matters are the business of doctors: just fix me. But those patients who take the bit of time needed to come to at least a basic understanding of their hearts do a lot better in terms of both short- and long-term recovery.
Your heart is an incredibly strong chunk of muscle a bit larger than a big man’s fist. From the moment of birth, it has pumped blood through the circulatory system to all parts of your body, never stopping neither day nor night. It will beat about 2.5 billion times over a lifetime, pumping 18,200 litres of blood daily. For years scientists, physicians and engineers have tried to build an artificial heart. Thus far they have not succeeded in creating one that works nearly as well as the original equipment. When you think of the complexity involved you can understand why. Imagine this virtually tireless machine pulsing through every minute of life from birth to death, never stopping for rest or repair. Amazing. But even more astounding is the way it works in conjunction with the needs of the entire body, responding to complex signals through physiologic electrical circuitry.
Let’s take a closer look. The heart is about 12.5 cm long, 10 cm wide, and 9 cm thick. It weighs less than a can of cola, about 285 to 340 grams in men and slightly less in women. Forget the Valentine’s Day symbol. The true shape is more like a cone. The right side aligns with the breastbone in the middle of your chest. Its top angles off to the left and ends in a point or apex at the left nipple.
Most of the heart is myocardium, coming from the Greek myo for muscle and kardia for heart. When most muscles in your body move, they act on direct orders from the brain. Not so for the heart. Instead of getting direction from the brain, an internal electrical system regulates heart rate, the pumping action.
Your entire heart comes enveloped in a thin, silky bag called the pericardium. Like any piece of machinery, the heart must be kept well lubricated. The pericardium contains fluid that oils the tissue surfaces of the heart and keeps it moving easily while contracting. On the inside walls of the heart a smooth protective layer of tissue, the endocardium, assists in keeping the organ protected.
Arteries and veins carry blood to and from the heart. The largest of the arteries is the aorta, attached to the left ventricle. From there, it snakes over the top of the heart and sends oxygen-rich blood off to your body through a system of increasingly smaller arteries, ultimately ending in tiny arterioles and then microscopic capillaries whose widths are not much larger than the blood cells they transmit. For the return trip, those cells are picked up by venules, and then pass on through a branching of veins and finally back to the heart. The exchange of oxygen and carbon dioxide takes place at the level of capillaries. Ultimately that’s the whole purpose: to carry oxygen to the body’s cells and to remove the carbon dioxide waste products. Along the way, of course, blood also carries nutrients and a vast chemical trove of hormones, electrolytes, neuro-transmitters and other substances vital to life.
While many mysteries remain as to just how the heart works, it’s basic structure is quite simple. The heart is divided into four chambers: the left and right ventricles on the bottom and the left and right atriums (atria), or holding areas, on the top. There are also four valves which make sure that once blood has entered a chamber it can’t flow backward and cause problems. Blood is meant to flow in one direction and one direction only. In fact, the two sides of the heart are separated by a tough wall of tissue called the septum.
All those parts work in beautiful, orchestrated harmony. The workhorse is the left ventricle, contracting to push bright red, oxygenated blood out to the body. It’s ten times thicker than the right to provide the needed musculature for sufficient contractions to get blood to all parts of the body.
Returning through the veins, or the venous system, “used” oxygen-depleted blood enters the heart through the superior and inferior vena cavas, simply the Latin words for “hollow veins”. These two main veins bring all blood back for re-oxygenating to the right atrium. When filled with blood, the right atrium pushes open the tricuspid valve and blood flows down into the right ventricle. That chamber, in turn, pumps blood through the pulmonary valve and into the pulmonary artery. It’s here that dark blood rushes into the lungs and exchanges carbon dioxide for fresh oxygen.
Blood with a full oxygen supply flows through the pulmonary vein into the left atrium and through the mitral valve into the left ventricle, where the whole cycle begins anew.
Everything works together. In fact, the complex system doesn’t work at all unless everything is in harmony. While the left ventricle fills with oxygenated blood, the right ventricle receives its supply from the upper chamber. The ventricles contract together to send the blood off through the appropriate arteries.
Timing, as in all things, is critical. Your heart has its own “pacemaker”, a specialised bundle of cardiac cells called the sinoatrial node. Located at the top of the right atrium, your natural pacemaker produces tiny electrical currents that cause the cells of the heart to contract.
Pressures within the chambers and vessels are of utmost importance, just as they would be in a boiler or your car’s radiator. Blood pressure is a way to measure the force of the blood against your arteries. Needless to say, high blood pressure puts excess wear and tear on your body’s “plumbing” just as it would in a boiler. We’ll get into a lot more detail about blood pressure and what we can do to control it in chapter 15.
Doctors refer to blood pressure as two numbers, as in 120 over 80. The upper, larger number is the systolic pressure and measures the heavy work being done by your ventricles, specifically the pressure at the moment the powerful left ventricle of the heart contracts. The lower figure, the diastolic pressure, is a measurement taken when the ventricles are between contractions and reflects the lowest constant pressure on your arteries as blood comes rushing through.
On average, your heart beats between 60 and 80 times each minute. When exercising, that number can reach 200, depending on your age, fitness and level of exertion. The important thing to consider is that the heart continues to function without much fanfare throughout your life. You really never notice it other than at those times when you might get a scare at a horror movie and your heart beats faster than usual.
All the heart asks in return for its efforts is the same oxygen-supplying blood it pumps to all the body’s other organs. Normally that blood comes through a system of arteries that crown the heart and are thus termed the coronary arteries. The four coronary arteries are the right coronary artery, the left main artery, the left anterior descending artery, and the circumflex artery. But if the heart doesn’t get the blood supply it needs through those vessels, problems begin.
*25/85/2*

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