Acenocoumarol

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STUDIES ON EVENING PRIMROSE OIL AND CHOLESTEROL
Evening primrose oil has an interesting effect on cholesterol levels. It will only bring down cholesterol levels if they are high, but it will have no effect on cholesterol levels if they are normal or low. As the starting cholesterol levels rise, so the relative potency of the GLA in evening primrose oil increases.
Evening primrose oil is clearly an effective cholesterol-lowering agent in those people with plasma cholesterol values above 5 mmol/1, in other words, in all but the lowest 20% of cholesterol levels.
Like other PUFAs, evening primrose oil either has no effect on HDL (high density lipoprotein) cholesterol or actually increases it. The cholesterol-lowering action of evening primrose oil is entirely because it is able to lower LDL (low density lipoprotein) cholesterol. It is the LDL cholesterol which is harmful and which needs to be lowered in order to reduce the risk of a heart attack. HDL cholesterol is desirable because it actually helps to transport cholesterol away from places where it may be harmful. Evening primrose oil has the very beneficial effect of raising the HDL/LDL ratio.
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