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Aralen (Chloroquine Phosphate)

Aralen (Chloroquine Phosphate)

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Other names: Chloroquine

ASPIRIN THERAPY: SIDE EFFECTS AND CAUTIONARY NOTES
Side effects
The most common side effect of high-dose aspirin therapy is stomach distress. Symptoms are usually minor and can be relieved by taking aspirin with meals.
Another common side effect is blood passed in tiny amounts daily in the stool. This is usually not dangerous, but it can lead to anemia.
Some people on high-dose aspirin therapy develop serious stomach problems such as gastritis and stomach ulcer. Fortunately, bleeding ulcers are infrequent. Anyone developing one of these problems needs to stop taking aspirin and begin treatment with special stomach medications. The medication misoprostal (Cytotec) helps prevent these side effects.
Cautionary Notes
Before starting aspirin therapy discuss the following with your physician:
• A history of allergy to aspirin or other anti-inflammatory medications. Symptoms of allergy include rash, hives, and swollen lips or eyelids. Wheezing and difficulty with breathing are rare and serious allergic responses.
• A history of asthma, nasal polyps, stomach ulcer, bleeding problems, colitis, kidney or liver problems.
• Any medications that you are presently taking. Of particular importance are blood thinners, diabetes medication, blood pressure pills, seizure medication, and over-the-counter pain medications.
While taking aspirin:
• Contact your physician promptly if you notice dark or tar-colored bowel movements, persistent indigestion or nausea, stomach pain that is relieved by eating.
• Never take more than one anti-inflammatory drug at a time. If your doctor prescribes a new NSAID, he or she will almost certainly take you off aspirin; if he or she fails to discuss this with you, you should ask about it. Do not take over-the-counter anti-inflammatory medications such as ibuprofen while you are taking high doses of aspirin. If your physician approves, acetaminophen (Tylenol) may be taken while you are taking aspirin. Unless you are instructed otherwise, you should take aspirin at mealtime to reduce indigestion and stomach irritation.
• Inform your dentist, surgeon, and anyone else performing health care procedures that you are on aspirin therapy.
• Avoid drinking alcohol and smoking because these practices increase your risk of developing an ulcer.
• Your doctor may periodically request blood tests for blood cell counts, kidney and liver tests, and tests for electrolytes (sodium and potassium) levels, as well as examine your stool for blood.
Pregnancy and breastfeeding. Aspirin should be avoided during pregnancy, particularly during the last trimester, unless specifically prescribed by your doctor. Aspirin therapy may affect the fetus or cause complications during labor and delivery.
Salicylates are excreted in breast milk, and therefore large doses of aspirin should be avoided while nursing.
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